Postdoctoral Position in X-ray Crystallography Structure of the endosomal ESCRT-I core complex Faculty of Life Sciences, University of Manchester, Manchester, UK
A postdoctoral position is available in the laboratory of Dr Lydia Tabernero to study the structural basis for the assembly of a protein complex that is essential for mitogenic receptor down regulation. The project will focus on understanding the core structure of the endosomal-sorting complex, ESCRT-I (Stefani et al., 2011, Curr. Biol. 21, 1245050).
The position is part of an on-going research collaboration between Dr Lydia Tabernero and Professor Philip Woodman directed towards understanding the molecular basis for the down-regulation of the epidermal growth factor receptor. This is a high-impact fast-moving basic research area with direct implications for bettering our understanding of a key cellular process that is disrupted in several diseases. The successful applicant will join a collaborative team, also involving the laboratories of Professor Philip Woodman and Dr Alan Roseman, and will use X-ray crystallography and other structural techniques.
The ideal candidate will have (or expect to gain shortly) a PhD in structural biology, and will have experience in recombinant protein expression and X-ray crystallography.
The post is full time for up to 24 months and can be available immediately.
Salary: £29,541 to £36,298 depending on experience
Closing date :19/03/2013
Further particulars and a full description of the project and job responsibilities can be found at: www.jobs.manchester.ac.uk
Informal enquiries can be made to Dr Lydia Tabernero, Lecturer:
Telephone: 0161 275 7794
The University of Manchester values a diverse workforce and welcomes applications from all sections of the community.