IRB Barcelona is seeking a talented and highly motivated Postdoctoral Researcher to join the Structural Bioinformatics and Network Biology group, led by Dr. Patrick Aloy, to work on Personalized Medicine. The candidate will work on the project “Cluster Emergente del Cerebro Humano” (CECH) funded by the Secretariat of Universities and Research of the Ministry of Business and Knowledge (Government of Catalonia) and by the European Regional Development Fund (FEDER).
The successful candidate shall be responsible for the implementation of a pipeline to collect and process biological big data, and to encapsulate it in the form of heterogeneous biological embeddings. Overall, a novel strategy will be developed to integrate the deluge of biological data in a format that is readily suitable for modern machine learning. Additionally, he/she will develop a General Connectivity Mapping (GCMap) strategy to link biological and chemical signatures from the Chemical Checker, so that the biological context of each small molecule can be incorporated as a descriptor. The added value of these biological descriptors will then be explored to identify therapeutic opportunities to treat complex diseases.
Required Experience
Education
Bachelor in Biosciences, or Engineering degree in Computer Sciences. PhD in Bioinformatics, or related areas.
Skills/experience
Previous experience in the processing and integration of multi-Omics data.
Strong publications record according to his/her career stage.
Excellent programming and scripting skills, with deep knowledge of Python.
Competent knowledge of databases management (e.g. postgresSQL and Neo4j).
Competent in the use of HPC queue systems, virtual machines (OpenNebula) and Grid Containers (Docker, Singularity).
Excellent interpersonal and communication skills.
Highly motivated.
Fluency in English.
Desirable Experience
Previous experience working on complex diseases and in an international environment.
Machine learning (including embedding techniques).
The closing date for this role is 31 March 2020. For more information and to apply, click here.
