Jobs in Structural Biology and Related Fields

Cryo-electron microscopy scientist, NeCEN

Leiden University, Leiden, Netherlands
Application deadline: 15 Sep 2019

NeCEN is looking for a highly talented scientist preferably experienced in cryo-electron microscopy who would like to contribute to the performance of an advanced cryo-EM centre at a world-class level.

You will maintain optimal equipment performance and collect high-quality data as part of a team. You will be primarily responsible for sample loading, alignment, and data acquisition on the two Titan Krios microscopes, a Talos L120C TEM and an Aquilos Cryo-FIB to prepare cryo-lamellae for tomography. Additionally, EM scientists at NeCEN are offered to perform collaborative research and technical development (approx. 20% of the time) to help ensure NeCEN remains at the forefront of electron microscopy.

Key responsibilities include:

  • Together with the other EM scientists, take care of the advanced cryo-EM microscope equipment with their ancillaries;
  • Ship, prepare, and load samples, align/tune microscopes prior to data collection, setup and oversee image acquisition, and evaluate data quality;
  • Communicate experimental details to users, assist with data analysis in the context of collaborative projects and write experimental methods for resulting publications;
  • Maintain ancillary equipment (cryo-plunger, glow discharger, etc.) and occasionally order consumables;
  • Explore and implement improved data-collection strategies, including testing new software and hardware;
  • Maintain accurate logs to monitor microscope performance, experimental conditions, usage, scheduling, and billing;
  • Consult with other cryo-EM experts in the region and internationally by participating in cryo-EM meetings and workshops;
  • Write clear documentation, establish facility procedures, and perform light administrative duties;
  • Willingness to occasionally work evenings and/or weekends to ensure maximal use of microscopes.

For more information and to apply, click here.

Leiden, Netherlands

Cryo-electron microscopy scientist, NeCEN