Service / Technology Instance

About Native Mass Spectrometry, Joensuu, Finland

UEF core facility offers two state-of-the-art mass spectrometers for versatile utilization of native mass spectrometry for studies of protein folding and assembly of biological macromolecules as well as for quantitative biological interaction studies with large dynamic range.

Instruments Available:

Bruker 12-T Solarix XR (FT-ICR) mass spectrometer, equipped with ESI, nanoESI, APPI and APCI ionizations. Key features: mass range (m/z), 70-15,000 (up to ca. 500 kDa); mass error (RMS), <100 ppb; sensitivity, nM level (direct infusion); MS/MS techniques: CID, ECD/EDD, IRMPD; Dionex 3000 nano/cap HPLC-system; microchip based nanoESI robot (Advion Triversa Nanomate).

Bruker timsTOF (TIMS-QTOF) mass spectrometer, equipped with ESI, nanoESI, APPI, APCI, GC-APCI, and DIP ion sources. Key features: mass range (m/z) 20-40,000; mass error (RMS): <0.5 ppm; ion mobility resolution up to 200; MS/MS techniques: CID; Dionex 3000 nano/cap HPLC-system and Bruker 456 GC system. Ion mobility separates ions based on their size and shape. TIMS = trapped ion mobility spectrometry.

Instruct Centre

University of Eastern Finland

Department of Chemistry & Biocenter Kuopio

Yliopistokatu 7

FI-80101, Joensuu

Finland

Native Mass Spectrometry, Joensuu, Finland

Contacts:

Janne Jänis
Janne Jänis
University of Eastern Finland
Login to contact
Mikko Laitaoja
Mikko Laitaoja
University of Eastern Finland
Login to contact