Confo Therapeutics are looking for a highly motivated individual to join their growing structural biology team as a specialist to lead and support their GPCR cryo-EM efforts. Confo has a unique technology which makes use of antibody VHH fragments or ConfoBodies™ to stabilise GPCRs in a particular biologically-active conformation, of interest as a superior starting point for protein structure determination and innovative H2L/SBDD process. Recently, Confo secured an exclusive license to the Megabody™ technology. Megabodies enable to produce high resolution cryo-EM structures of membrane proteins, overcoming current protein size limitations and potential preferential orientation issues in the study of GPCRs via cryo-EM. Confo is currently located on the Technology Park in Zwijnaarde/Ghent and on the VUB campus in Brussels. More information about Confo’s technology and strategy can be found here.
The candidate should have a Ph.D. in a field related to structural biology, such as cell biology, biochemistry or biophysics. Experience in the membrane protein structural biology - either or both X-ray crystallography and electron microscopy - ideally at the postdoctoral level and/or industrial experience. Moderate or extensive EM experience is preferred. The candidate should be an energetic team player with the ability to model enthusiasm and motivate others to excellence. Applicants should be ambitious to grow their cryo-EM expertise in the membrane protein field and a project leader in drug discovery projects.
For more information and to apply, click here.
