Plex Pharmaceuticals, a biotechnology company which is developing novel drugs targeting protein misfolding and aggregation, has an opening for a full-time Scientist.
The successful candidate will contribute to drug discovery efforts by performing compound screening in biochemical, cell-based, and ex vivo assays, as well as assisting in assay development for further characterization of compounds. Under supervision the Scientist will:
• Perform enzyme assays, binding assays, reporter assays, SDS-PAGE protein electrophoresis, Western blot analysis, and ELISAs
• Use appropriate cellular models for neurodegenerative and other diseases for assaying cell death, gene expression, protein aggregation and other biomarker assays
• Develop and troubleshoot new biochemical and cell-based assays
• Identify and develop strategies to contribute to drug discovery projects and grant applications
• Support day-to-day needs of the lab and the company
Education Qualification and Experience:
• PhD or MS in biology, neuroscience, or related field with 1-3 or 4-6 years’ experience, respectively, either in an academic or pharmaceutical setup
• Demonstrated proficiency in protein biochemistry
• Experience in cell culture and cell-based assays. Preference will be given to candidates with experience in biochemical, cellular and ex-vivo models of protein misfolding and aggregation
• Understanding and knowledge of small-molecule drug discovery and development process
• Must be eager to learn and take initiative on new projects
• Knowledgeable with a broad range of laboratory equipment
• Experience in Microsoft Excel and other Microsoft Office applications is required
• Experience and knowledge in use of GraphPad Prism software
• Sound critical thinking capabilities, with the ability to work independently to plan experiments, interpret and analyze data
• Strong organizational skills and attention to detail
• Good oral and written communication skills
• Willingness to work in a dynamic, challenging, flexible and fast paced environment
• A self-motivated, independent worker who can identify needs and take initiative to address them
• Strong commitment to work as a team and strong interpersonal skills
Plex is a casual, friendly work environment with an attractive benefits package which includes paid time off, employee stock options, company paid medical & dental plans.
To be considered for this position please submit your Resume/CV with a cover letter and three references to hr@plexpharma.com
