Confo Therapeutics are looking for a highly motivated individual to join their growing structural biology team as a specialist to lead and support their GPCR cryo-EM efforts. Confo has a unique technology which makes use of antibody VHH fragments or ConfoBodies™ to stabilise GPCRs in a particular biologically-active conformation, of interest as a superior starting point for protein structure determination and innovative H2L/SBDD process. Recently, Confo secured an exclusive license to the Megabody™ technology. Megabodies enable to produce high resolution cryo-EM structures of membrane proteins, overcoming current protein size limitations and potential preferential orientation issues in the study of GPCRs via cryo-EM. Confo is currently located on the Technology Park in Zwijnaarde/Ghent and on the VUB campus in Brussels. More information about Confo’s technology and strategy can be found here.
Applicants should have an advanced degree (BSc/MSc) and at least 3 year experience in a related field in a biotech environment. Candidates should be an expert in molecular biology, recombinant protein expression using insect/mammalian systems and purification methods. The ideal candidate would have also extensive experience in biochemical/biophysical characterisation/screening and protein engineering. Applicants should be highly collaborative, self-motivated and team-oriented individual.
For more information and to apply, click here.
