King's College London, London, United Kingdom
Application deadline: 23 Jan 2014
are invited for a Postdoctoral Research Associate position in the Chemistry Department within the School of Natural and Mathematical Sciences at King’s College London to conduct research in structural biology of macromolecules using NMR spectroscopy and other biophysical techniques in the group of Dr Rivka Isaacson.
Our research group uses biophysical techniques to characterise macromolecular structure and interactions. In this BBSRC-funded project we will use NMR spectroscopy, X-ray crystallography, Isothermal Titration Calorimetry (ITC), Microscale thermophoresis (MST) and other methods to characterise machinery that sorts and targets hydrophobic proteins as they emerge from the ribosome. This work has long-term implications for the understanding and treatment of hormone-related diseases such as prostate and ovarian cancer and polycystic ovary syndrome.
Successful candidates must hold a PhD in Chemistry, Biochemistry or related subject, and demonstrate experience in Nuclear Magnetic Resonance spectroscopy, X-ray crystallography, protein production and biophysical techniques, preferably including ITC and MST.
The post will be based in Britannia House at the Guy’s Campus. The duration is for 3 years. The starting date is March 2014.