Jobs in Structural Biology and Related Fields


Postdoctoral Research Associate - Cryo-Electron Microscopy


Diamond Light Source Ltd, Harwell, United Kingdom
Application deadline: 30 Mar 2020


An opportunity has become available for a highly motivated PDRA to carry out their own innovative research in the development of new methods in high-throughput cryo-electron tomography. Research will concentrate on enhancing the throughput and applicability of the technique to complex biological problems, frequently utilising samples prepared onsite by focused ion beam milling.

This role will form part of our outstanding eBIC and BioImaging group which includes five Titan Krios microscopes all equipped with Falcon III and Gatan Quantum K2/K3 detectors. A Talos, Glacios, Scios and Aquilos dual-beam are also onsite along with the B24 cryo structured illumination microscope for correlative work.

You will utilise and benefit from Diamond's existing expertise in data collection and data processing in X-ray imaging.

You will also have the opportunity to play an active role in interacting and potentially collaborating with the rapidly expanding EM community based at Harwell such as ePSIC, The Research Complex at Harwell (e.g. CCP-EM), and The Rosalind Franklin Institute, as well as other collaborations.

This opportunity provides a unique position to perform novel studies integrating state-of-the-art technologies with new method development. These studies will systematically explore new frontiers in cryoET.

Further responsibilities will include:

Performing experiments, analysing data and publishing results;
Supporting users in performing experiments, including data analysis and training;
Assisting eBIC staff with EM commissioning, instrument upgrade, development and testing of new equipment and software.
Keeping up with latest results and research directions internationally;
A flexible approach to working hours is required, along with occasional UK and overseas travel including some overnight stays.

About You

You should hold an appropriate science degree and a PhD in a structural biology or an electron microscopy related field.

Previous knowledge or experience at postgraduate level in cryoEM is desirable, as is experience with Windows/Linux/Unix, scripting (E.g. Python) or programming, and experience with operating a FIB-SEM.

You will be an enthusiastic scientist with a demonstrable record of accomplishment in conducting high quality original research.

You will demonstrate excellent interpersonal, communication and presentational skills to interact with staff and facility users at all levels.

For more information and to apply for this role, click here.

Harwell, United Kingdom

Postdoctoral Research Associate - Cryo-Electron Microscopy