Our research group at Karolinska Institutet (http://jovinelab.org) is looking for a postdoctoral fellow to investigate the molecular mechanism of egg-sperm interaction at fertilization by single-particle cryo-EM.
The position, funded by a long-term grant from the Knut and Alice Wallenberg foundation, will benefit from a close collaboration with Alexey Amunts laboratory at SciLifeLab (https://www.scilifelab.se/researchers/alexey-amunts/) as well as easy access to local cryo-EM facilities (Stockholm node of the Cryo-EM Swedish National Facility (https://www.scilifelab.se/facilities/cryo-em/) and KI 3D-EM (https://ki.se/en/research/3d-em)) that together include 3 x Titan Krios with K3 detectors, a Talos Arctica with K2 and a Talos L120C with Ceta-D. Joining our groups will thus provide a unique opportunity to build upon the strengths of two complementary labs and state-of-the-art technology, in order to tackle one of the most fundamental questions in biology and understand how life begins.
Candidates must hold (or be about to receive) a Ph.D. degree and have significant hands-on experience in structural biology. Although proven experience in single-particle cryo-EM and knowledge of helical reconstruction will constitute an advantage, excellent candidates with experience in X-ray crystallography and a strong interest in learning cryo-EM will also be taken into consideration. Additionally, previous experience in mammalian cell expression as well as purification and biochemical characterization of glycoproteins will be considered an asset. At least one first author paper in a high-quality international peer-reviewed journal, fluency in English (both written and oral), good team spirit and a very strong personal drive to excel in science are required.
For more information about this position and to submit an application through the KI MyNetwork recruitment system (deadline 3 March 2020), click here.