There is an immediate availability in the laboratory of Jamaine Davis for an enthusiastic postdoc who is interested in the molecular recognition of protein complexes essential for genome maintenance. The successful candidate will investigate DNA repair protein structure and complex assembly mechanisms using X-ray crystallography and/or single-particle cryo-EM, in addition to performing functional assays. The work in the lab is generally geared towards developing a mechanistic understanding of the DNA damage response using functional and structural techniques. The ideal candidate for this position is a protein biochemist who has experience in X-ray crystallography and wants to gain experience in cryo-EM.We are located on the campus of Meharry Medical College within vibrant Nashville, aka Music City. Nashville has been rated #12 on Forbes list of best places for businesses and careers. Our lab is also a member of the Center for Structural Biology at Vanderbilt University (http://structbio.vanderbilt.edu/faculty/davis.php),where we have access to the Vanderbilt Cryo Electron Microscopy Facility (V-CEM). The V-CEM facility houses high-resolution transmission electron microscopes (TEMs) and cameras needed to collect data for single particle analysis and tomography.
Qualifications and experience: Candidates should hold a Ph.D. in a relevant field and have a solid background in protein biochemistry. Candidates with prior experience in protein expression/purification, mutagenesis, structure determination (e.g., X-ray, NMR) and protein-nucleic acid interaction are preferred. Experience with cryo-EM is advantageous. Excellent verbal and written English communication skills, and ability to work in close collaboration with other researchers are required.
Qualified applicants should send a cover letter, CV, and the names of three references by email to Jamaine Davis at jdavis@mmc.edu.
