A post-doctoral position is available immediately at Upstate Medical University for a highly-motivated individual to perform NIH-funded work on the structure and function of the erlin1/2 complex; see Wright and Wojcikiewicz (2016) Prog. Mol. Biol. Trans. Sci. 141, 141-159; Pearce at al. (2009) J. Biol. Chem. 284, 10433-10445. Primary goals will be to express and solve the structure of the erlin proteins, to utilize cryo-EM to generate a high-resolution structure of the erlin1/2 complex and use CRISPR/Cas 9-based approaches to define the interface between activated IP3 receptors and the erlin1/2 complex.
The successful candidate will join a highly active lab focused on signaling via IP3 receptors in mammalian cells. Applicants must have a Ph.D. degree in biological sciences with strengths in structural biology, biochemistry and cell biology. The candidate is expected to drive forward the project, act semi-independently, compile and analyze and write up data for publication, and work co-operatively with others.
For consideration, please send your CV, three references and other relevant information to Professor Wojcikiewicz via the application form.
Please quote job number 050295
