Application deadline: 07 Feb 2014
Post-doctoral position in structure-function studies on plant-selective herbicides Weed control by selective herbicides is an important instrument to secure global food supply. Recent structural and biochemical studies in our lab have identified new selective inhibitors of a protein essential for plant growth and development. In a collaborative research project funded by the Ministry of Innovation, Science and Research of the state NRW, we aim to establish a detailed structural and functional view of the mode of action of these substances. Other work packages of the interdisciplinary research project will address the effect of these substances on typical soil bacteria and study response dynamics of photosynthesis and whole plant growth to the localized or generalized application of these compounds.
and the associated X-Ray Facility and Crystal Farm of the Heinrich Heine University has facilities for protein crystallography (e.g., Bruker-AXS Prospector X8, Incoatec Microfocus beam, Formulatrix Rockimager imaging system, crystallisation robots Beckman Biomek 3000, Matrix Hydra II, Formulatrix NT8). Our lab is also well equipped with instruments for biochemical and biophysical analysis (e.g., microscale thermophoresis, fluorescence spectroscopy, UV/VIS spectroscopy).
We are looking for a highly motivated individual with a strong interest in biochemical and structural characterization of protein-ligand complexes to complement our team. The ideal candidate will have experience and a successful track record of in biochemistry and protein crystallography.
The position is available immediately, with funding available for two years at a salary according to the German Public Service salary scale EG 13 TV-L. Please send a cover letter discussing your interests in the laboratory and the project as well as your CV and the names of 2 individuals as references to Professor Dr. Georg Groth, Institute of Biochemical Plant Physiology, Heinrich Heine University, Duesseldorf, 40204.