Jobs in Structural Biology and Related Fields

Postdoctoral posiiton in Cryo-EM

Institute of Organic Chemistry and Biochemistry (IOCB), Prague, Czech Republic

Application deadline: 01 Apr 2020

Job description
A fellowship-funded postdoc position is open in Dr Sebastian Zoll’s group at the Institute of Organic Chemistry and Biochemsitry (IOCB) in Prague. Dr Zoll’s group is using a combination of biochemical, biophysical, immunological and structural biology techniques to understand the mechanisms of host-pathogen interactions. The succesful candidate will use Cryo-EM to determine the structure of a viral capsid protein in complex with its cellular receptor. As part of this process the applicant will generate monoclonal antibody and nanobody libraries as tools as well as for therapeutic applications.

Requirements

• PhD in structural biology using Cryo-EM as the main tool. Expertise in grid preparation, microscope operation and data processing in RELION is essential. Knowledge in X-ray crystallography and SAXS is a bonus but not necessary.
• Experience in expression construct design, protein purification and biophysical techniques to analyse protein-protein interactions (ITC or SPR).

The project is supported by a multidisciplinary network of international collaborators and provides excellent opportunities to receive additional training in foreign host institutions.
The fellowship is granted for one year with possible extension by one more year. The earliest starting date is May 2020. For further information, click here.

How to apply?
Please send a short motivation statement (max. 500 words) and a copy of your CV to sebastian.zoll@uochb.cas.cz