A 2 years postdoctoral position funded by the Agence National de la Recherche (ANR) is available in the group of Dr. Laurent Terradot (@LaurentTerradot) in the Unit Molecular Microbiology and Structural Biochemistry(MMSB) of the Institut de Biologie et Chimie des Protéines (IBCP, CNRS-University of Lyon), Lyon, France.
They are interested in structure function of protein-protein complexes involved in Helicobacter pyloripathogenesis. This bacteriumis a major human pathogen that can causehuman diseases such as ulcers and gastric cancers. The position is dedicated to the understanding ofHelicobacter pylori Type IV secretion systemby the determination of several protein-protein complexes by X-ray crystallography or Cryo-EM. Preliminary data are already available for several protein samples.For more information on the project see Koelblen et al., 2017; Bergé and Terradot, 2017; Bergé, Wakmsan and Terradot, 2017, Bats et al., 2018; Zhao et al., 2019).
The IBCP is well equipped for cell biology, molecularbiology and biochemistryand Structural Biologyand belongs to a larger campus (Lyon Biopole; Center for Infectiology), giving access to state-of-the-art core facilities in areas. The group has regular access to synchrotron beam timeand Cryo-EM. Lyon is avibrant, historical French city and is aworld-excellence center in infectiology.
Working language of the laboratory is English. They are looking for enthusiastic and self-motivated individuals with a strong backgroundinprotein purificationand Structural biology. Experience in the study of complexes would be a plus. Knowledge in Macromolecular Crystallography and/or Cryo-EM would be considered an advantage but is not mandatory.
Proposed starting date: February 2020
Salary is according to the CNRS french guidelines and should be between 2500-3200 euros gross monthly according to experience.
Interested candidates must apply online on the CNRS website with a CV, reference letter(s) and a short summary of your experience/motivation