A fully-funded Postdoc position is available in the Pasteur Institute, in Paris. Their goal is to study the structure and function of a new class of DNA polymerases involved in DNA replication, and decipher the molecular mechanisms they evolved to efficiently replicate DNA in molecular machines (replisomes). This integrated structural study will use primarily Cryo-EM approaches.
The Unit for Structural Dynamics of Macromolecules at the Pasteur Institute is a well published and highly dynamic research environment that applies a multidisciplinary research strategy including structural biology, biochemistry, and biophysics to address fundamental questions about the molecular mechanisms of DNA replication. The laboratory is situated at the Pasteur Institute in Paris that has an outstanding range of facilities and instrumentation, including a state-of-the-art Titan Kryos equipped with a K3 camera, a F20 (200kV) microscope equipped with a Falcon 2 camera, and two T12 (120 kV) microscopes. Additional resources for specimen preparation and image processing are in place.
Applicants should hold a PhD in the area of structural biology, biochemistry, or molecular biology. Experience in cryo-electron microscopy, and data processing would be a plus, but not an absolute pre-requisite.
Please contact Dr. Ludovic Sauguet with informal inquiries about the position (lsauguet@pasteur.fr)
