Jobs in Structural Biology and Related Fields

PhD Research Fellowship in Structural Biology and Drug Development

Oslo, Norway
Application deadline: 31 Mar 2019

Job description

A 3 year PhD fellowship is available in the Group of Structural Biology and Drug Development (Luecke group) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO).

The Group for Structural Biology and Drug Development investigates medically relevant proteins and protein complexes using biophysical, biochemical and structural approaches.  The projects aim at understanding structure-function relationships with an emphasis on drug discovery.  We employ a variety of biochemical and biophysical techniques (x-ray crystallography, single particle cryo electron microscopy, DSF, ITC, SPR, HDX-MS, SAXS, molecular dynamics simulations etc.).  Externally funded projects include inhibitor discovery targeting the Helicobacter pylori pH acclimation system (a pH-gated urea channel and a cytoplasmic urease), and discovery of compounds that reactivate p53 cancer mutants in vitro and in vivo.  Additional projects are available.

The PhD student will also benefit from career development programs offered both at UiO, the Norwegian BioCat initiative as well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.

Qualification requirements

  • Applicants must hold a Master’s degree or equivalent in biochemistry, chemistry, molecular biology or a related.
  • Hands-on experience with purification of proteins and assembly of protein complexes.
  • Ability to independently perform experiments, analyze and interpret the results.
  • Excellent interpersonal/communication skills.
  • Fluent oral and written communication skills in English.

  • Ability to operate as a team player in a multi-disciplinary environment.
How to apply

The application must include

  • cover letter statement of motivation and research interests

  • CV (summarizing education, positions and academic work)
  • copies of educational certificates (academic transcripts only)
  • a complete list of publications and academic works, with a brief summary of the candidate’s contribution to each paper
  • list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)

The application with attachments must be delivered through the electronic recruiting system, please follow this link. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.


About the position and the project: Professor Hartmut "Hudel" Luecke,

About administrative aspects of the application: HR adviser Ragni Indahl,

Oslo, Norway

PhD Research Fellowship in Structural Biology and Drug Development