The Fischer lab at St. Jude Children’s Research Hospital is recruiting a graduate student for a structural biology project that exploits protein dynamics for ligand discovery against pediatric cancer targets.
The student will be part of a young interdisciplinary team that uses structural biology (crystallography, NMR), protein biochemistry, and single-molecule methods to characterize dynamic, disease-relevant protein states. By finding ligands against those flexible protein states, and revealing allosteric networks we can explore new ways to modulate protein malfunction in disease.
The group is part of the Department of Chemical Biology and Therapeutics, and Structural Biology at St. Jude Children’s Research Hospital. With ongoing investments into exceptional structural biology, chemical biology and computational facilities.
This work will provide a solid introduction to current opportunities in structure-based ligand discovery with relevance for both academia and industry. With its excellent core facilities, highly interactive and supportive environment St. Jude Children’s Research Hospital is a great place to do research and build a career while living in an affordable city.
Accompanying courses will be taken in conjunction with the Department of Pharmaceutical Sciences at the University of Tennessee Health Science Center.
Minimum admission requirements:
- a BS or MS degree in pharmacy, chemistry, biology, mathematics, engineering, or other appropriate disciplines.
- a minimum Grade Point Average of 3.0
- a combined Graduate Record Examination score (verbal and quantitative) of at least 300
- proof of proficiency in English (e.g. TOEFL)
Please direct your questions and application package including a cover letter, current CV, and 3 letters of reference to: Dr. Marcus Fischer (marcus.fischer@stjude.org) by February 3rd, 2020.
Online application deadline is March 15th for admission to the Fall Semester starting in August 2020.
For further information, click here.
