Jobs in Structural Biology and Related Fields


Multidisciplinary group with expertise in molecular biology, protein biochemistry, X-Ray crystallography and high-resolution fluorescence microscopy


Cell Biology and Biophysics Unit, NINDS Porter Neuroscience Research Center Building 35, Room 3B-203 35 Convent Drive, MSC 3700 Bethesda, MD 20892-3700, United States
Application deadline: 01 Dec 2018


They are currently seeking an outstanding individual to join their team as Senior Scientist in Cryo-Electron Microscopy at the National Institute of Neurological Disorders and Stroke in Bethesda. The successful candidate will join a multidisciplinary group with expertise in molecular biology, protein biochemistry, X-Ray crystallography and high-resolution fluorescence microscopy with a mission to provide molecular insights into important cytoskeletal regulators. The lab has regular access to a state-of-the art cryo-EM facility which includes a Titan Krios with a K2 direct electron detector with energy filter and will soon add a 200 kV Talos Arctica.

The Senior Scientist will:

  • Bring innovative structural biology technologies, with a focus on cryo-EM as a method for novel protein structure determination
  • Design and conduct experiments for all aspects of structure determination by Cryo-EM, including grid preparation, data collection and processing and 3-D model building.
  • Work closely with molecular biologists, protein scientists, biophysicists as part of an integrated structural biology effort
  • Interface with the central trans-NIH cryo-EM facility for optimal data collection strategies
  • Training, assisting and overseeing scientists in the group in sample preparation for cryo-EM, data collection and image processing
  • Contribute to the strategic planning of our group in cryo-EM
Qualifications
  • A minimum of a Ph.D. or equivalent is required
  • Postdoctoral experience in structural biology or related field is required
  • A minimum of 3 years of research experience in single particle cryo-electron microscopy in industry or an academic institution is required
  • Deep scientific expertise in structural biology and high-resolution structure determination is required
  • Strong record of external publications and presentations is required
  • Experience in scientific programming and ability to work with the latest relevant software packages
  • Experience in cryo-electron tomography a plus
  • Skills in working and communicating with scientists at all levels
Salary and benefits are generous and commensurate with research experience and accomplishments. The DC area is a great place to live with access to many cultural and outdoors activities. NINDS offers a rich and diverse scientific environment and the resources on campus are unparalleled. More information can be found at:https://neuroscience.nih.gov/ninds/rm_lab/  and https://neuroscience.nih.gov/ninds/Home.aspx

 

To apply: Please send a cover letter, curriculum vitae, bibliography, a one-page statement of research experience relevant to this position and the names of three references to Dr. Antonina Roll-Mecak ( Antonina@mail.nih.gov ) Applications will be considered until December 1, 2018

Cell Biology and Biophysics Unit, NINDS Porter Neuroscience Research Center Building 35, Room 3B-203 35 Convent Drive, MSC 3700 Bethesda, MD 20892-3700, United States

Multidisciplinary group with expertise in molecular biology, protein biochemistry, X-Ray crystallography and high-resolution fluorescence microscopy