Structural Biologist Position at at Brown University, USAThe Deaconescu Lab at Brown University has one opening for a structural biologist. The laboratory's interests lie primarily in stress responses, with particular emphasis on responses to DNA damage and the mechanochemistry of DNA-based motors. We utilize a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For examples of work, please see Vemu et al. Science (2018), Le TT et al. Cell (2018), Deaconescu et al. Photochemistry and Photobiology (2017), Kutter et al. JMB (2016), Szyk et al, Cell (2014), Deaconescu et al., PNAS (2012), Szyk et al., NSMB (2012) and Deaconescu et al., TIBS (2013).
A successful candidate should have an established track-record of publications in peer-reviewed journals. Solid experience with protein biochemistry (including their purification from E.coli/yeast expression, functional characterization and assay development) is desirable. Prior knowledge of crystallography and/or single-particle electron microscopy is essential. Crystals/data at various stages of the structure determination process are available for immediate work. Responsibilities include crystal freezing, data collection and processing, obtaining and interpreting maps (X-ray or cryo-EM), model building, refinement and deposition of structures. Additionally the candidate will participate in the teaching and training of other lab members. Overall responsibilities and compensation will depend on qualification and performance.Must be highly motivated and work independently as well as in a team. Excellent spoken and written English are required. New Ph.D. graduates are encouraged to apply.
Interested candidates should send a CV, one page research experience summary and contact information for three references to alexandra_deaconescu@brown.edu. Salary and starting date are negotiable. Brown University, an Ivy League school, is located less than one hour away by train from Boston. Lab webpage: https://deaconesculab.com
