Our main research interests are (1) in vivo structural study of important biological processes/nanomachines through electron cryo-tomography; and (2) development of correlative light and electron microscopy methods and further their applications. (Our lab website)
The successful candidate is expected to have a strong background in cryo-EM, X-ray crystallography, super-resolution microscopy, physics, or computer programming, and, most importantly, is inspired by the importance and FUN of in situ structural determination.
Our institute is fully equipped for cutting-edge electron cryo-tomography: a 300keV Titan Krios G3i cryo-EM with Volta phase plate, Quantum energy filter and K3 direct detector, a cryo-FIB-SEM, a cryogenic fluorescence light microscope, a comprehensive sample preparation and screening facility (EMRL), and several state-of-the-art computer clusters for data processing.
If you are interested in joining us and having a lot of fun together while building up a strong publication record, please send your CV and a cover letter to me directly at (yi-wei.chang@pennmedicine.upenn.edu).
