The workshop for the hydrodynamic and thermodynamic analysis of biological macromolecules and their interactions: multi-method approaches and global data analyses is organised by IBS (Institut de Biologie Stucturale).
The opening of the field of biophysical measurements to new users creates the need for basic and advanced training courses covering fundamental knowledge of the instrumental methods, practice in setting-up and performing experiments, and data analysis and interpretation. The aim of the course is to provide theoretical, practical, and data analysis training in several complementary modern methods, mainly analytical ultracentrifugation (AUC), isothermal titration calorimetry (ITC), surface plasmon resonance (SPR), biolayer interferometry (BLI).The course will provide brief theoretical introduction to the biophysical concepts underlying these methods, practicalities to prepare samples and set-up experiments, experimental demonstrations performed on state-of-art instruments present in the IBS/EPN site, introduction to basic and advanced data analysis methods. Emphasis will be put on the combined analysis of datasets coming from different methods, using the programs SEDFIT, SEDPHAT, EVILFIT and NITPIC, which are free available. The main objective is to learn about data analysis of even complex interacting systems, using a global analysis of multiple data obtained with one or different techniques.
The workshop will take place in the European Photon & Neutron Science campus (EPN) of Grenoble from the 26 - 30 January 2020.
More information will be available closer to the time.