Our H2020 Projects

Instruct-Ultra launched in 2017 to deepen and widen access to innovative high-end structural biology techniques within Europe and beyond. It aims to accelerate and expand membership of Instruct-ERIC to new member countries, with the possibility to trial access beforehand. 

Structural Biology is currently in the midst of a revolution enabled by significant advances in the tools such as ultra-high field NMR and advances in synchrotron sources. Instruct-ULTRA is well placed to exploit new technologies and build capacity within both academic and industry settings in response to accelerating demand. 

The launch of pilot projects will aid further development and refinement of new innovations in structural biology techniques, allowing niche bespoke methods to find broader application across the wider scientific and medical research community.


  • Achieve long‐term sustainability by expanding membership to provide servic valued in the global context
  • Enhanced delivery of world‐leading structural biology services to academic and industrial users
  • Raise standards and competence in structural biology in Europe and globally

The Instruct-ULTRA project is supported and staffed by Instruct-ERIC, and receives funding from the European Union’s Horizon 2020 research and innovation programme.


CORBEL is an initiative of eleven biological and medicalresearch (BMS-RI) infrastructures to create a platform for harmonised useraccess to biological and medical technologies, biological samples and dataservices required by cutting-edge biomedical research. 


  • To provide access to resources and services that enable cutting-edge biomedicalresearch. Instruct will lead work to develop a common access framework thatfacilitates user access to services and resources across the involved RIs. 
  • To deliver the implementation of core, sustainable services necessary to supportinter BMS ESFRI data standardization, integration, management, deposition and access. 
  • To identify the competency requirements of staff in BMS RIs for the newlyidentified services proposed by this application and use organising a pilot training programme 


West-life is an initiative under the Virtual ResearchEnvironment (VRE) e-Infrastructure programme (EINFRA-9-2015). 


  • To pilot an infrastructure for storing and processing data to support the growing use ofcombined techniques.
  • To develop automated and integrated data management and processing pipelines forstructural biology 
  • To expand the work of the previous WeNMR and BioMedBridges EU projects in order to coverall aspects of structural biology to serve the Instruct community.  



iNEXT is an infrastructure for NMR, EM and X-rays for Translational Research. it can support researchers from all EU and associated countries but also (in a more limited capacity) from international labs, to perform a variety of structural biology experiments with a translational research component, in the fields of X-ray crystallography, SAXS, NMR, EM, light imaging and Biophysics for Macromolecular Interactions.


  • Providing access to state-of-the-art infrastructures for structural biology.
  • Use the research infrastructures for translating fundamental research into bio-scientific applications.
  • Stimulate access for non-structural biologists. 


OPEN SESAME project will ensure optimal exploitation of the Synchrotron light for Experimental Science and Applications in the Middle East (SESAME) light source. With this aim, OPEN SESAME has three key objectives: 

1. To train SESAME staff in the storage ring and beamline instrumentation technology, research techniques and administration for optimal use of a modern light source facility.

2. To build-up human capacity in Middle East researchers to optimally exploit SESAME’s infrastructure.

3. To train SESAME staff and its user community in public outreach and corporate communications, and to support SESAME and its stakeholders in building awareness and demonstrating its socio-economic impact to assure longer term exploitation.

The project directly addresses the INFRASUPP-2016-2017 call to support SESAME. OPEN SESAME is well aligned to the broader scope of the work programme with activities that will have a lasting impact on a reinforced European Research Area, and particularly in strengthening international cooperation for research infrastructures with a key Region located close to Europe.

The project has been developed closely with SESAME, its Directors and international Training Advisory Committee. The OPEN SESAME consortium is composed of ten European institutes (six light sources, The Cyprus Institute, CERN, CNRS and Instruct) along with SESAME itself.


The AARC2 project aims to address policy and technical interoperability gaps that prevent researchers from accessing the whole research and infrastructure service portfolio with one login (SSO), regardless of where this takes place in the ecosystem. By enabling SSO among infrastructures, scientists worldwide will be able (using their existing credentials) to seamlessly and securely access infrastructure services, reducing administrative overhead and improving international collaboration.

AARC2 builds on the work successfully done by the AARC project, which is laying out the foundations for the AAI to become a transversal infrastructure to serve the needs of all European (and beyond) scientists across all research areas. The proposed work also takes into account the research infrastructures and e-infrastructures requirements gathered during the AARC project and the requirements that have emerged from the use-cases included in this proposal.


  • The main objectives of the AARC2 project are:
  • To enable federated access in selected research communities
  • To assist research communities to map their requirements to a concrete service offer
  • To support research infrastructures and e-infrastructures to implement the recommendations of the AARC Blueprint Architecture and Policy Framework
  • To offer different levels of training as appropriate to enable communities to deploy and adopt AARC/AARC2 results when designing new services
  • To enhance the blueprint of the integrated architecture by supporting additional features


TRANSVAC2is the follow-up project to its successful predecessor project TRANSVAC, the European Network of Vaccine Research and Development funded under FP7. The TRANSVAC2 consortium comprises a comprehensive collection of leading European institutions that propose to further advance with the previous initiative towards the establishment of a fully operational and sustainable European vaccine R&D infrastructure. 

TRANSVAC2 will support innovation for both prophylactic and therapeutic vaccine development based on a disease-overarching and one-health approach, thereby optimising the knowledge and expertise gained during the development of both human and animal vaccines. This will be achieved by bridging the translational gap in biomedical research, and by supporting cooperation between public vaccine R&D institutions of excellence, related initiatives and networks in Europe, and industrial partners. TRANSVAC2 will complement and integrate with existing European research infrastructures in both the public and private sectors.

The impact of TRANSVAC2 will be maximised by two external advisory bodies. An independent Scientific & Ethics Advisory Committee will provide recommendations surrounding scientific-technical and ethical issues, whereas the coordination of TRANSVAC2 with other related initiatives and the further promotion of the long-term stability of a European vaccine R&D infrastructure will be supported by a Board of Stakeholders comprising representatives of policy and decision makers, industry associations and European infrastructures.


Past H2020 Projects

For information about historical H2020 structural biology projects which Instruct-ERIC has participated in, click here.