Service / Technology

Nanobody Discovery

Nanobody discovery


Nanobodies are the small (15 kDa) and stable single-domain fragments harboring the full antigen-binding capacity of camelid heavy chain–only antibodies. Nanobodies are exquisite chaperones for crystallizing membrane proteins, multiprotein assemblies, transient conformational states and intrinsically disordered proteins. Nanobodies can also be used for other applications in structural biology. Domain-specific Nanobodies have been used in single-particle electron microscopy (EM) to track these domains in particle projections. Because Nanobodies can be functionally expressed as intrabodies in eukaryotic cells, these single-domain antibodies can also be used to track their targets inside a living cell.

Service/Technology Instances

 Els Pardon email hidden
 Jan Steyaert email hidden

Instruct has 1 centre offering Nanobody Discovery across Europe.

Click on the map to navigate around. Discover the centres near you by clicking the Instruct icons.

Terms of Use | Terms of Submission | Privacy Policy | Copyright © 2018 The University of Oxford | Powered by ARIA