Biocenter Oulu Infrastructure for Structural Biology
Finnish Infrastructure for Integrative Structural Biology is formed by three Centers of Excellence at the Universities of Helsinki, Oulu and Eastern Finland. We provide expert-supported access to services and technologies in sample preparation, characterization, and structure determination. The Finnish structural biology community is represented by the national consortium Instruct-FI, which is forming a national link to the Instruct-ERIC.
Biocenter Oulu fosters the expertise and infrastructure for protein crystallography including crystal data management and for molecular biophysics. The technologies for protein crystallography include protein crystallisation and in-house data collection capabilities, which are linked to the development of the IceBear software. IceBear is used to view the results of protein crystallization experiments and to track crystal handling and sample shipment to other data collection facilities. Structural studies can be complemented by a range of biophysical methods for sample characterization and for studying macromolecular interactions including research of enzymes as biocatalysts.
Biocenter Oulu is a strategic focus institute of the University of Oulu in the city of Oulu, situated in northern Finland. The Instruct platform consists of Biocenter Oulu core facilities for protein crystallography and molecular biophysics.
University of Oulu services are located at Aapistie 7 of the Kontinkangas campus near the university hospital. The site can be reached from the Oulu airport by taxi or a city bus.
Biocenter Oulu Protein Crystallography core facility offers crystallization using nanoliter dispensers and a collection of commercial and self maintained crystallization screens. Crystallization is followed using the IceBear software and remote access to monitor the experiments can be provided following the visit.
Biocenter Oulu Molecular Biophysics core facility offers multiple technologies for analysing secondary structure and stability of biological macromolecules, biomolecular interactions and enzyme kinetics.